Outcome of patients with fibrolamellar hepatocellular carcinoma.

Title
Outcome of patients with fibrolamellar hepatocellular carcinoma.

Source
Cancer. 106(6):1331-8, 2006 Mar 15.

BACKGROUND:

Fibrolamellar hepatocellular carcinoma (FL-HCC) is a rare variant of hepatocellular carcinoma, has distinct pathologic features, and typically occurs in young patients without underlying hepatitis or cirrhosis.

CONCLUSIONS:

FL-HCC occurs in a distinctly different population of patients than common hepatocellular carcinoma (HCC), and patients with FL-HCC generally fare better after complete resection. These tumors have a relatively indolent tumor biology, and late recurrences are common. Repeat resections for recurrence should be considered given the lack of other effective treatment options.